Open perforator hypothesis

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Coronary recanalization in anterior myocardial infarction: the open perforator hypothesis.

OBJECTIVE Patent perforators, noninvasively imaged by transthoracic color-Doppler echocardiography, may reflect adequate reperfusion in anterior myocardial infarction (MI). BACKGROUND The Thrombolysis In Myocardial Infarction (TIMI) classification may not fully reflect adequate myocardial reperfusion in MI. METHODS We studied 61 patients with anterior MI undergoing thrombolysis (n = 28), pr...

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The Open Artery Hypothesis

There is considerable clinical and experimental evidence of the benefit of late reperfusion of infarct-related arteries, referred to as the open artery hypothesis, in patients with acute myocardial infarction who presented too late to salvage at-risk ischemic myocardium. In addition to myocardial salvage, reperfusion of the infarct-related artery prevents infarct expansion, reduces development ...

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Perforator Relocation in Free Style Local Perforator Flaps

Local perforator flaps have evolved over the time to provide complete and stable coverage of soft tissue defects. Technical advances and experience with the perforator flaps have allowed the harvest of local perforator flaps in a free style manner by offering greater freedom in flap selection. We have proposed a technical modification in the harvest of a perforator flap by relo-cating the perfo...

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New insights into the open artery hypothesis.

Factors Affecting Left Ventricular Remodeling Early coronary artery reperfusion is clearly the most important therapy for acute ST segment elevation myocardial infarcts. Early reperfusion reduces myocardial infarct size and in so doing helps to prevent or minimize deleterious consequences of a large myocardial infarction, including infarct expansion (thinning and dilation of the infarct), subse...

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Open circular billiards and the Riemann hypothesis.

A comparison of escape rates from one and from two holes in an experimental container (e.g., a laser trap) can be used to obtain information about the dynamics inside the container. If this dynamics is simple enough one can hope to obtain exact formulas. Here we obtain exact formulas for escape from a circular billiard with one and with two holes. The corresponding quantities are expressed as s...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2002

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(02)02106-x